LHB 抗体
Quick Overview for LHB 抗体 (ABIN7794912)
抗原
See all LHB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Human Luteinizing Hormone (LH)-Purified (Clone 196)
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特异性
- Mouse Anti-Human Luteinizing Hormone Beta (LH=?) (Clone 196) recognizes Human Luteinizing Hormone Beta. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Luteinizing hormone (LH) is a hormone synthesized and secreted by gonadotropes in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle stimulating hormone (FSH) it is necessary for proper reproductive function. In the female, an acute rise of LH - the LH surge - triggers ovulation. In the male, where LH had also been called Interstitial Cell Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a glycoprotein. Each monomeric unit is a protein molecule with a sugar attached to it, two of these make the full, functional protein. Its structure is similar to the other glycoproteins, FSH, TSH, and hCG. The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two disulfide bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta sub unit of hCG and both stimulate the same receptor, however, the hCG beta subunit contains an additional 24 amino acids, and both hormones differ in the composition of their sugar moieties. The different composition of these oligosaccharides affects bioactivity and speed of degradation. The biologic half-life of LH is 20 minutes, shorter than that of FSH (3-4 hours) or hCG (24 hours).
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免疫原
- Purified Recombinant Human LH-beta (>98%)
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亚型
- IgG
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anti-Luteinizing Hormone beta Polypeptide (LHB) (AA 23-141) antibody
LHB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) (AA 21-141) antibodyLHB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) (AA 21-141) antibodyLHB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) antibodyLHB 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal LHb-1214 unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) antibodyLHB 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) (AA 21-141) antibodyLHB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) antibodyLHB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) (Internal Region) antibodyLHB 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) (AA 78-104), (C-Term) antibodyLHB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14582 unconjugated
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限制
- 仅限研究用
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浓度
- 1 μg/mL
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缓冲液
- This purified antibody is supplied in 0.01 M phosphate buffered saline (PBS), pH 7.4, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For long term storage freeze working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
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- LHB (Luteinizing Hormone beta Polypeptide (LHB))
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别名
- Luteinizing Hormone Beta
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物质类
- Hormone
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背景
- LH,
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途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
抗原
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